SCHEMBL2957871

SCHEMBL2957871

O=CC(O)(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.47
TDP1 Q9NUW8 2/20 0.43
ALDH1A1 P00352 2/20 0.43
MAPK1 P28482 1/20 0.43
SRC P12931 1/20 0.43
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.41
POLB P06746 1/20 0.41
CYP3A4 P08684 1/20 0.41
PARP1 P09874 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C19 P33261 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CES2 O00748 2/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
CA12 O43570 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27548907 0.82 CES1 (0.42) CES1TDP1ALDH1A1MAPK1SRC
SCHEMBL1123626 0.82 CES1 (0.46) CES1TDP1ALDH1A1MAPK1SRC
SCHEMBL15376730 0.81 CYP2C9 (0.47) TDP1ALDH1A1MAPK1TSHRHSD17B10
SCHEMBL22518412 0.79 CES1 (0.47) CES1TDP1ALDH1A1MAPK1SRC
SCHEMBL7535663 0.79 ALDH1A1 (0.50) ALDH1A1HSD17B10POLBMAPTNAPRT
SCHEMBL7539727 0.78 HPGD (0.47) ALDH1A1TSHRHSD17B10CYP3A4MAPT
SCHEMBL5426260 0.78 MAOB (0.46) CES1TDP1ALDH1A1MAPK1SRC
SCHEMBL30102520 0.78 CES1 (0.48) CES1TDP1ALDH1A1MAPK1SRC
SCHEMBL7694890 0.78 CYP1A2 (0.43) TDP1ALDH1A1MAPK1TSHRHSD17B10
SCHEMBL7195473 0.77 LMNA (0.39) TDP1ALDH1A1SRCTSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11028121-B2 Multisignal labeling reagents and processes and uses therefor ENZO LIFE SCIENCES, INC. (US) 2021-06-08 US disclosed
US-20200270297-A1 MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR ENZO LIFE SCIENCE, INC. (US) 2020-08-27 US disclosed
US-10647740-B2 Multisignal labeling reagents and processes and uses therefor ENZO LIFE SCIENCE, INC. (US) 2020-05-12 US disclosed
US-10640529-B2 Multisignal labeling reagents and processes and uses therefor ENZO LIFE SCIENCES, INC. (US) 2020-05-05 US disclosed
CN-110526821-A A kind of synthetic method of p formylbenzoic acid WUXUE YANGTAI CHEMICAL CO LTD 2019-12-03 CN disclosed
US-20180127455-A1 MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR Enzo Life Science, Inc., c/o Enzo Biochem, Inc. (US) 2018-05-10 US disclosed
US-20180127456-A1 MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR Enzo Life Science, Inc., c/o Enzo Biochem, Inc. (US) 2018-05-10 US disclosed
US-9884889-B2 Multisignal labeling reagents and processes and uses therefor ENZO LIFE SCIENCES, INC. (US) 2018-02-06 US disclosed
US-20160025716-A1 MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR Enzo Life Science, Inc., c/o Enzo Biochem, Inc. (US) 2016-01-28 US disclosed
US-9156986-B2 Multisignal labeling reagents and processes and uses therefor ENZO LIFE SCIENCES, INC. (US) 2015-10-13 US disclosed
WO-2006054888-A2 CURABLE LIQUID COMPOSITION, CURED FILM, AND ANTISTATIC LAMINATE JSR CORPORATION (JP) 2006-05-26 WO disclosed
WO-2006041289-A1 RADIATION CURABLE COATING COMPOSITION DSM IP ASSETS B.V. (NL) 2006-04-20 WO disclosed
US-20060084716-A1 Radiation curable coating composition DSM IP ASSETS B.V. (NL) 2006-04-20 US disclosed
EP-1304924-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS Bayer Aktiengesellschaft (DE) 2003-05-02 EP disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed
WO-2002005646-A2 COMPOSITIONS FOR REPELLING CRAWLING INSECTS S.C. JOHNSON & SON, INC. (US) (US) 2002-01-24 WO disclosed
CN-1067978-C Preparation method of methyl p-formylbenzoate QINGDAO CHEMICAL INST (CN) 2001-07-04 CN disclosed
CN-1169982-A Preparation method of methyl p-formylbenzoate QINGDAO CHEMICAL INDUSTRY INST (CN) 1998-01-14 CN disclosed
US-3947494-A HEAVY METAL CATALYST, OXIDATION OF XYLENES STANDARD OIL COMPANY (US) 1976-03-30 US disclosed
US-3944601-A OXIDATION OF XYLENE, ACETIC ACID, CATALYST, HYDROBROMIC, SULFURIC OR PHOSPHORIC ACID STANDARD OIL COMPANY (US) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10647740-B2 Multisignal labeling reagents and processes and uses therefor PCNA, LIG4, LIG1 CES1 4459/4885TDP1 311/4885ALDH1A1 3760/4885
US-10640529-B2 Multisignal labeling reagents and processes and uses therefor PCNA, LIG4, LIG1 CES1 4459/4885TDP1 311/4885ALDH1A1 3760/4885
US-20180127455-A1 MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR PCNA, LIG4, LIG1 CES1 4459/4885TDP1 311/4885ALDH1A1 3760/4885
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 CES1 1995/4885TDP1 3063/4885ALDH1A1 1488/4885
US-20180127456-A1 MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR PCNA, LIG4, LIG1 CES1 4459/4885TDP1 311/4885ALDH1A1 3760/4885
US-11028121-B2 Multisignal labeling reagents and processes and uses therefor PCNA, LIG4, LIG1 CES1 4459/4885TDP1 311/4885ALDH1A1 3760/4885
US-20200270297-A1 MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR PCNA, LIG4, LIG1 CES1 4459/4885TDP1 311/4885ALDH1A1 3760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.