Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 9/20 | 0.76 |
| ▸ | PGR | P06401 | 8/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.76 |
| ▸ | LMNA | P02545 | 6/20 | 0.76 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | HTR1A | P08908 | 1/20 | 0.76 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.56 |
| ▸ | AR | P10275 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42575 | 0.92 | NR3C1 (0.78) | NR3C1PGRCYP3A4LMNAABCB11 | |
| Flunisolide SCHEMBL4351 | 0.86 | CYP3A4 (1.00) | NR3C1PGRCYP3A4LMNAABCB11 | |
| Flunisolide SCHEMBL66051 | 0.86 | CYP3A4 (1.00) | NR3C1PGRCYP3A4LMNAABCB11 | |
| Flunisolide SCHEMBL30994800 | 0.86 | CYP3A4 (1.00) | NR3C1PGRCYP3A4LMNAABCB11 | |
| Flunisolide SCHEMBL5187487 | 0.86 | CYP3A4 (1.00) | NR3C1PGRCYP3A4LMNAABCB11 | |
| Flunisolide SCHEMBL8810954 | 0.86 | CYP3A4 (1.00) | NR3C1PGRCYP3A4LMNAABCB11 | |
| Flunisolide SCHEMBL13026142 | 0.86 | CYP3A4 (1.00) | NR3C1PGRCYP3A4LMNAABCB11 | |
| Flunisolide SCHEMBL5493687 | 0.86 | CYP3A4 (1.00) | NR3C1PGRCYP3A4LMNAABCB11 | |
| Flunisolide SCHEMBL13662143 | 0.86 | CYP3A4 (1.00) | NR3C1PGRCYP3A4LMNAABCB11 | |
| Flunisolide SCHEMBL13602384 | 0.86 | CYP3A4 (1.00) | NR3C1PGRCYP3A4LMNAABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295489-A | Compositions, devices and methods for treating respiratory disorders | 呼吸解决方案股份有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117279681-A | Product delivery device and method | 呼吸解决方案股份有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-117295489-A | Compositions, devices and methods for treating respiratory disorders | 呼吸解决方案股份有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-117279681-A | Product delivery device and method | 呼吸解决方案股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116133664-A | Ophthalmic inserts containing glucocorticoids | 视觉治疗股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-110177780-B | Pyrimidine compounds containing acidic groups | 阿普罗斯治疗公司 | 2022-11-01 | — | — | CN | disclosed |
| US-20100191215-A1 | PRESSURE PULSE ACTUATING DEVICE FOR DELIVERY SYSTEMS | BY-PASS ,INC. (US) | 2010-07-29 | — | — | US | disclosed |
| WO-2008152639-A2 | PRESSURE PULSE ACTUATING DEVICE FOR DELIVERY SYSTEMS | BYPASS, INC. (US) | 2008-12-18 | — | — | WO | disclosed |
| EP-1549371-A2 | NEBULIZER HAVING A SOLVENT AND AN INERT SUBSTRATE IMPREGNATED WITH A PHARMACEUTICAL INGREDIENT | Collegium Pharmaceutical, Inc. (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004022132-A2 | NEBULIZER HAVING A SOLVENT AND AN INERT SUBSTRATE IMPREGNATED WITH A PHARMACEUTICAL INGREDIENT | COLLEGIUM PHARMACEUTICAL, INC. (US) | 2004-03-18 | — | — | WO | disclosed |
| US-20040045546-A1 | Pharmaceutical delivery system for oral inhalation through nebulization consisting of inert substrate impregnated with substance (S) to be solubilized or suspended prior to use | PEIRCE MANAGEMENT, LLC | 2004-03-11 | — | — | US | disclosed |