Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 9/20 | 0.61 |
| ▸ | ECE1 | P42892 | 6/20 | 0.57 |
| ▸ | IL1RN | P18510 | 9/20 | 0.57 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | EDNRA | P25101 | 1/20 | 0.52 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.52 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30254765 | 0.96 | ERAP2 (0.63) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL30051713 | 0.95 | ECE1 (0.63) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL30697236 | 0.93 | MAGI3 (0.58) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL30185726 | 0.93 | ERAP2 (0.59) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL30415073 | 0.93 | ERAP2 (0.59) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL29822316 | 0.92 | ECE1 (0.58) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL30465916 | 0.92 | ERAP2 (0.64) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL32667969 | 0.91 | ERAP2 (0.60) | ERAP2ECE1IL1RNERAP1EDNRA | |
| SCHEMBL30465873 | 0.91 | ERAP2 (0.62) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL29533774 | 0.91 | ERAP2 (0.62) | ERAP2ECE1IL1RNERAP1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115636870-B | Cyclic color-threo-valyl-leucinyl peptide with hepatoma cytotoxicity and alpha-glucosidase inhibitory activity and preparation method thereof | 安徽农业大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-115636870-B | Cyclic color-threo-valyl-leucinyl peptide with hepatoma cytotoxicity and alpha-glucosidase inhibitory activity and preparation method thereof | 安徽农业大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-115636870-A | Cyclochromo-threo-valine-leucine peptide with hepatoma cytotoxicity and alpha-glucosidase inhibition activity and preparation method thereof | 安徽农业大学 | 2023-01-24 | — | — | CN | disclosed |
| CN-115636870-A | Cyclochromo-threo-valine-leucine peptide with hepatoma cytotoxicity and alpha-glucosidase inhibition activity and preparation method thereof | 安徽农业大学 | 2023-01-24 | — | — | CN | disclosed |