Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.63 |
| ▸ | ECE1 | P42892 | 6/20 | 0.61 |
| ▸ | IL1RN | P18510 | 7/20 | 0.57 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.57 |
| ▸ | ACE | P12821 | 2/20 | 0.57 |
| ▸ | EDNRA | P25101 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051713 | 0.98 | ECE1 (0.63) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL30102898 | 0.96 | ERAP2 (0.61) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL30415073 | 0.96 | ERAP2 (0.59) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL30185726 | 0.96 | ERAP2 (0.59) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL29822316 | 0.95 | ECE1 (0.58) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL29533774 | 0.94 | ERAP2 (0.62) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL29538468 | 0.94 | ERAP2 (0.69) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL30786597 | 0.93 | ECE1 (0.59) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL8776396 | 0.92 | ECE1 (0.70) | ERAP2ECE1IL1RNERAP1ACE | |
| SCHEMBL7622341 | 0.92 | ECE1 (0.70) | ERAP2ECE1IL1RNERAP1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115716864-B | Cyclic color-valyl-leucinyl peptide with hepatoma cytotoxicity and alpha-glucosidase inhibitory activity and preparation method thereof | 安徽农业大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-115716864-B | Cyclic color-valyl-leucinyl peptide with hepatoma cytotoxicity and alpha-glucosidase inhibitory activity and preparation method thereof | 安徽农业大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-115716864-A | Cyclo-valine-leucine peptide with hepatotoxicity and alpha-glucosidase inhibitory activity and preparation method thereof | 安徽农业大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-115716864-A | Cyclo-valine-leucine peptide with hepatotoxicity and alpha-glucosidase inhibitory activity and preparation method thereof | 安徽农业大学 | 2023-02-28 | — | — | CN | disclosed |