Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 7/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103083 | 0.94 | BRD4 (0.41) | CACNA1HMEN1KMT2AGRM2BRD4 | |
| SCHEMBL30103066 | 0.92 | CACNA1H (0.40) | CACNA1HAVPR1BGRIN2BGRIN1KDM1A | |
| SCHEMBL24785079 | 0.90 | CACNA1H (0.40) | CACNA1HAVPR1BGRIN2BGRIN1BRD4 | |
| SCHEMBL30018338 | 0.90 | CACNA1H (0.40) | CACNA1HAVPR1BGRIN2BGRIN1BRD4 | |
| SCHEMBL24785835 | 0.88 | CACNA1H (0.38) | CACNA1HGRIN2BGRIN1KDM1ATNIK | |
| SCHEMBL30103113 | 0.88 | CACNA1H (0.38) | CACNA1HGRIN2BGRIN1KDM1ATNIK | |
| SCHEMBL24785847 | 0.86 | BRD4 (0.40) | CACNA1HMEN1KMT2AGRM2BRD4 | |
| SCHEMBL30103081 | 0.86 | BRD4 (0.40) | CACNA1HMEN1KMT2AGRM2BRD4 | |
| SCHEMBL24785849 | 0.86 | BRD4 (0.42) | CACNA1HGRM2BRD4CNR1ROCK2 | |
| SCHEMBL24784529 | 0.86 | KMT2A (0.45) | MEN1POLBKMT2AGRM2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |