Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 7/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103022 | 0.94 | CACNA1H (0.41) | BRD4CACNA1HGRM2ROCK2MEN1 | |
| SCHEMBL24785847 | 0.92 | BRD4 (0.40) | BRD4CACNA1HPTGESMCHR1GRM2 | |
| SCHEMBL30103081 | 0.92 | BRD4 (0.40) | BRD4CACNA1HPTGESMCHR1GRM2 | |
| SCHEMBL24785849 | 0.92 | BRD4 (0.42) | BRD4CACNA1HPTGESMCHR1GRM2 | |
| SCHEMBL30018129 | 0.90 | BRD4 (0.41) | BRD4CACNA1HMCHR1GRM2PKM | |
| SCHEMBL24785366 | 0.90 | BRD4 (0.41) | BRD4CACNA1HMCHR1GRM2PKM | |
| SCHEMBL24785813 | 0.88 | GRIN2B (0.38) | BRD4CACNA1HPTGESMCHR1GRM2 | |
| SCHEMBL30018152 | 0.88 | GRIN2B (0.38) | BRD4CACNA1HPTGESMCHR1GRM2 | |
| SCHEMBL30103066 | 0.86 | CACNA1H (0.40) | CACNA1HGRM2ROCK2MEN1KMT2A | |
| SCHEMBL24785454 | 0.86 | BRD4 (0.41) | BRD4CACNA1HGRM2ROCK2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |