Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.37 |
| ▸ | NEK2 | P51955 | 4/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785825 | 1.00 | KDM4E (0.39) | KDM4EMEN1LMNAKMT2AGRIN2B | |
| SCHEMBL24785815 | 0.94 | GRIN2B (0.38) | KDM4EMEN1LMNAKMT2AGRIN2B | |
| SCHEMBL30103097 | 0.94 | GRIN2B (0.38) | KDM4EMEN1LMNAKMT2AGRIN2B | |
| SCHEMBL30103113 | 0.92 | CACNA1H (0.38) | GRIN2BCACNA1HKDM1ADHODHGRIN1 | |
| SCHEMBL24785835 | 0.92 | CACNA1H (0.38) | GRIN2BCACNA1HKDM1ADHODHGRIN1 | |
| SCHEMBL30103059 | 0.89 | KDM4E (0.40) | KDM4EGRIN2BCACNA1HALKBH1GRK6 | |
| SCHEMBL30103066 | 0.88 | CACNA1H (0.40) | KDM4EMEN1LMNAKMT2AGRIN2B | |
| SCHEMBL24785054 | 0.86 | GRIN2B (0.38) | GRIN2BKDM1AGRM5GRIN1 | |
| SCHEMBL24785813 | 0.86 | GRIN2B (0.38) | KDM4EGRIN2BCACNA1H | |
| SCHEMBL30018152 | 0.86 | GRIN2B (0.38) | KDM4EGRIN2BCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |