Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785815 | 1.00 | GRIN2B (0.38) | GRIN2BKDM4EL3MBTL1MEN1LMNA | |
| SCHEMBL24785825 | 0.94 | KDM4E (0.39) | GRIN2BKDM4EMEN1LMNAKMT2A | |
| SCHEMBL30103031 | 0.94 | KDM4E (0.39) | GRIN2BKDM4EMEN1LMNAKMT2A | |
| SCHEMBL30018152 | 0.92 | GRIN2B (0.38) | GRIN2BKDM4EL3MBTL1PTGIRALDH1A1 | |
| SCHEMBL24785813 | 0.92 | GRIN2B (0.38) | GRIN2BKDM4EL3MBTL1PTGIRALDH1A1 | |
| SCHEMBL24785847 | 0.88 | BRD4 (0.40) | KDM4EMEN1LMNAKMT2ACACNA1H | |
| SCHEMBL30103081 | 0.88 | BRD4 (0.40) | KDM4EMEN1LMNAKMT2ACACNA1H | |
| SCHEMBL30103113 | 0.86 | CACNA1H (0.38) | GRIN2BCACNA1HDHODH | |
| SCHEMBL24785835 | 0.86 | CACNA1H (0.38) | GRIN2BCACNA1HDHODH | |
| SCHEMBL24785368 | 0.84 | ALKBH1 (0.40) | KDM4ELMNAPTGIRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |