Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | MARS1 | P56192 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | ACLY | P53396 | 2/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785361 | 1.00 | DHODH (0.41) | DHODHGRM2MARS1CHRM5SRC | |
| SCHEMBL30103044 | 0.89 | AXL (0.40) | GRM2CHRM5SRCACLY | |
| SCHEMBL24785362 | 0.89 | AXL (0.40) | GRM2CHRM5SRCACLY | |
| SCHEMBL21458263 | 0.88 | EGLN1 (0.47) | DHODHMARS1EGLN1ACLY | |
| SCHEMBL30843281 | 0.88 | EGLN1 (0.47) | DHODHMARS1EGLN1ACLY | |
| SCHEMBL24785015 | 0.86 | CYP11B1 (0.40) | DHODHMARS1CTRCPTGER1KMO | |
| SCHEMBL30018091 | 0.86 | CYP11B1 (0.40) | DHODHMARS1CTRCPTGER1KMO | |
| SCHEMBL30103059 | 0.83 | KDM4E (0.40) | GRM2 | |
| SCHEMBL12584570 | 0.83 | PTGER4 (0.41) | DHODHGRM2CHRM5EGLN1ACLY | |
| SCHEMBL24785433 | 0.82 | DHODH (0.38) | DHODHEGLN1PTGER1KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |