Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | SGK1 | O00141 | 1/20 | 0.37 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24785362 | 1.00 | AXL (0.40) | AXLACLYCHRM5PLA2G2ASLC6A4 | |
| SCHEMBL30843297 | 0.89 | NPBWR1 (0.44) | ACLYPLA2G2ASLC6A4SLC6A3CNR1 | |
| SCHEMBL30103098 | 0.89 | DHODH (0.41) | ACLYCHRM5GRM2SRC | |
| SCHEMBL24785361 | 0.89 | DHODH (0.41) | ACLYCHRM5GRM2SRC | |
| SCHEMBL21458333 | 0.89 | NPBWR1 (0.44) | ACLYPLA2G2ASLC6A4SLC6A3CNR1 | |
| SCHEMBL24785022 | 0.87 | PLA2G2A (0.40) | PLA2G2ASLC6A4SLC6A3CNR1KDM4E | |
| SCHEMBL30103125 | 0.87 | PLA2G2A (0.40) | PLA2G2ASLC6A4SLC6A3CNR1KDM4E | |
| SCHEMBL24784624 | 0.86 | CACNA1H (0.39) | ACLYPLA2G2AGRM2 | |
| SCHEMBL30103038 | 0.86 | CACNA1H (0.39) | ACLYPLA2G2AGRM2 | |
| SCHEMBL24785432 | 0.85 | MCHR1 (0.36) | PLA2G2AKDM4EMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |