Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | HCK | P08631 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103070 | 0.89 | ALDH1A1 (0.48) | PDE10AKDM4EALDH1A1SYKNPC1 | |
| SCHEMBL19876647 | 0.75 | CLK4 (0.52) | PAX8PIK3CAGRM5GRM4KDM4E | |
| SCHEMBL11620358 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1SYKCD274HPGD | |
| SCHEMBL15674480 | 0.74 | PDGFRB (0.48) | KDM4EALDH1A1SYKNPC1GLA | |
| SCHEMBL17151138 | 0.71 | S1PR1 (0.43) | GRM4KDM4EALDH1A1SYKNPC1 | |
| SCHEMBL29501232 | 0.71 | FEN1 (0.56) | PIK3CAGRM4KDM4EALDH1A1CD274 | |
| SCHEMBL4114679 | 0.71 | SYK (0.56) | ALDH1A1SYKNPC1GAARAB9A | |
| SCHEMBL19841856 | 0.71 | LRRK2 (0.42) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL14341094 | 0.71 | PDE10A (0.49) | PAX8EGFRPDE10AGRM5KDM4E | |
| SCHEMBL9806866 | 0.71 | ALDH1A1 (0.46) | PDE10AKDM4EALDH1A1NPC1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448913-A | Bicyclic compounds for the treatment of EP2, EP4 receptor mediated diseases | 武汉人福创新药物研发中心有限公司 | 2022-12-09 | — | — | CN | disclosed |