Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5513936 | 0.89 | TAAR1 (0.45) | TAAR1LMNADRD1HRH4HRH3 | |
| SCHEMBL5518091 | 0.89 | TAAR1 (0.45) | TAAR1LMNADRD1HRH4HRH3 | |
| SCHEMBL5513930 | 0.89 | TAAR1 (0.45) | TAAR1LMNADRD1HRH4HRH3 | |
| SCHEMBL30063100 | 0.82 | TAAR1 (0.47) | TAAR1LMNADRD1HRH4HRH3 | |
| SCHEMBL25308726 | 0.81 | LMNA (0.48) | TAAR1LMNADRD1HRH4HRH3 | |
| SCHEMBL1566074 | 0.81 | LMNA (0.48) | TAAR1LMNADRD1HRH4HRH3 | |
| SCHEMBL25309758 | 0.81 | LMNA (0.48) | TAAR1LMNADRD1HRH4HRH3 | |
| SCHEMBL417603 | 0.81 | LMNA (0.48) | TAAR1LMNADRD1HRH4HRH3 | |
| SCHEMBL5519586 | 0.81 | TDP1 (0.54) | TAAR1LMNAHRH4HRH3CTSL | |
| SCHEMBL5527189 | 0.80 | HRH4 (0.43) | TAAR1LMNAHRH4HRH3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097138-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | Avila Therapeutics, Inc. (US) | 2022-12-07 | — | — | EP | disclosed |