Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.35 |
| ▸ | MPO | P05164 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23702605 | 1.00 | NOTUM (0.42) | NOTUMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL14955783 | 0.87 | NOTUM (0.48) | NOTUMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL15652439 | 0.79 | NOTUM (0.42) | NOTUMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL221069 | 0.79 | ADORA2A (0.42) | NOTUMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL387290 | 0.79 | MAPT (0.47) | NOTUMKDM4EALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL11484961 | 0.77 | MAPT (0.46) | NOTUMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL14955628 | 0.75 | ALDH1A1 (0.40) | NOTUMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL30880520 | 0.75 | KAT6A (0.46) | NOTUMKDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL12012868 | 0.75 | NR2E1 (0.46) | NOTUMKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL3400745 | 0.74 | NOTUM (0.48) | NOTUMKDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115698020-B | Macrocyclic RIP 2-kinase inhibitors | 昂科迪塞恩精密医药公司(OPM) | 2025-02-25 | — | — | CN | disclosed |
| EP-4097110-A1 | MACROCYCLIC RIP2-KINASE INHIBITORS | Oncodesign S.A. (FR) | 2022-12-07 | — | — | EP | disclosed |