Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 8/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 4/20 | 0.32 |
| ▸ | KDR | P35968 | 3/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407871 | 0.89 | ADK (0.46) | ADKSLC29A1CHEK1RETKDR | |
| SCHEMBL30104038 | 0.82 | DYRK3 (0.46) | ADKRETKDRSRC | |
| SCHEMBL16236485 | 0.78 | ADK (0.42) | ADKSLC29A1CHEK1RETKDR | |
| SCHEMBL16236551 | 0.77 | ADK (0.41) | ADKSLC29A1CHEK1RETSRC | |
| SCHEMBL20162965 | 0.77 | ADK (0.41) | ADKSLC29A1CHEK1SRCMEN1 | |
| SCHEMBL30037220 | 0.77 | ADK (0.41) | ADKSLC29A1CHEK1SRCMEN1 | |
| SCHEMBL16236609 | 0.74 | ADK (0.46) | ADKSLC29A1CHEK1MEN1NR2F2 | |
| SCHEMBL3605358 | 0.74 | ADK (0.49) | ADKSLC29A1CHEK1SRCMEN1 | |
| SCHEMBL16236652 | 0.73 | ADK (0.39) | ADKSLC29A1CHEK1MEN1NR2F2 | |
| SCHEMBL20162872 | 0.73 | ADK (0.39) | ADKSLC29A1CHEK1MEN1NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220380375-A1 | SUBSTITUTED AROMATIC FUSED RING DERIVATIVE AND COMPOSITION COMPRISING SAME, AND USE THEREOF | SHENZHEN TARGETRX, INC. (CN) | 2022-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220380375-A1 | SUBSTITUTED AROMATIC FUSED RING DERIVATIVE AND COMPOSITION COMPRISING SAME, AND USE THEREOF | SRC, TH, RET | ADK 331/4885SLC29A1 1532/4885CHEK1 934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.