Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 4/20 | 0.41 |
| ▸ | CMA1 | P23946 | 2/20 | 0.41 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | TDP2 | O95551 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16291500 | 0.81 | SMYD3 (0.43) | SMYD3EIF2AK2KDRAURKBPLK1 | |
| SCHEMBL29878803 | 0.81 | SMYD3 (0.43) | SMYD3EIF2AK2KDRAURKBPLK1 | |
| SCHEMBL13650417 | 0.74 | AHR (0.44) | SMYD3AHRCMA1EIF2AK2KDR | |
| SCHEMBL19153946 | 0.74 | AHR (0.44) | AHRCMA1EIF2AK2KDRCHEK1 | |
| SCHEMBL30809183 | 0.74 | AHR (0.53) | AHRCMA1EIF2AK2KDRCHEK1 | |
| SCHEMBL659822 | 0.74 | AHR (0.53) | AHRCMA1EIF2AK2KDRCHEK1 | |
| SCHEMBL5310732 | 0.73 | GAA (0.47) | CYP11B1CYP11B2 | |
| SCHEMBL30459851 | 0.72 | SMYD3 (0.59) | SMYD3AHRCMA1PLK1CRBN | |
| SCHEMBL21941431 | 0.70 | AHR (0.41) | AHRCMA1EIF2AK2KDRCHEK1 | |
| SCHEMBL669630 | 0.70 | EIF2AK2 (0.44) | AHRCMA1EIF2AK2KDRAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4061373-A1 | METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE | Angion Biomedica Corp. (US) | 2022-09-28 | — | — | EP | disclosed |