Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335073 | 0.76 | MMP12 (0.49) | ALDH1A1MAPTPKMMMP12MGLL | |
| SCHEMBL14358971 | 0.76 | MMP12 (0.49) | GAAALDH1A1MAPTPKMMMP12 | |
| SCHEMBL12002280 | 0.76 | MMP12 (0.57) | ALDH1A1MAPTMMP12KMT2ANR3C2 | |
| SCHEMBL29879244 | 0.76 | MMP12 (0.49) | GAAALDH1A1MAPTPKMMMP12 | |
| SCHEMBL3579328 | 0.76 | NR3C2 (0.46) | GAAALDH1A1MAPTPKMMMP12 | |
| SCHEMBL2797549 | 0.74 | MMP12 (0.46) | GAAALDH1A1MAPTPKMMMP12 | |
| SCHEMBL24307579 | 0.74 | ASPH (0.34) | KMT2A | |
| SCHEMBL30104082 | 0.73 | SMYD3 (0.44) | CYP11B1CYP11B2 | |
| SCHEMBL18237508 | 0.73 | MMP12 (0.49) | ALDH1A1MAPTMMP12KMT2ANR3C2 | |
| SCHEMBL532793 | 0.72 | GAA (0.71) | GAAALDH1A1MAPTPKMMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007016610-A2 | ANTIBACTERIAL AGENTS | GLAXO GROUP LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |