SCHEMBL30104089

SCHEMBL30104089

Brc1cc(-c2ccccc2)c2c(c1-c1ccccc1)-c1cccc3cccc-2c13

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
MAPK1 P28482 4/20 0.42
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.41
CASP1 P29466 2/20 0.41
CASP7 P55210 2/20 0.41
TP53 P04637 2/20 0.41
HPGD P15428 1/20 0.41
HIF1A Q16665 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ATM Q13315 1/20 0.41
CES2 O00748 1/20 0.34
BCHE P06276 1/20 0.34
CES1 P23141 1/20 0.34
MCL1 Q07820 1/20 0.34
CYP3A4 P08684 1/20 0.34
PABPC1 P11940 1/20 0.34
DNMT1 P26358 1/20 0.34
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24067755 1.00 ALDH1A1 (0.42) ALDH1A1MAPK1TSHRHSD17B10CASP1
SCHEMBL24191541 0.91 ALDH1A1 (0.38) ALDH1A1MAPK1TSHRHSD17B10CASP1
SCHEMBL30104100 0.91 ALDH1A1 (0.38) ALDH1A1MAPK1TSHRHSD17B10CASP1
SCHEMBL24191185 0.90 HDAC4 (0.41) ALDH1A1MAPK1TSHRHSD17B10CASP1
SCHEMBL30104107 0.90 HDAC4 (0.41) ALDH1A1MAPK1TSHRHSD17B10CASP1
SCHEMBL2158220 0.86 ALDH1A1 (0.47) ALDH1A1MAPK1TSHRHSD17B10CASP1
SCHEMBL17014606 0.84 ALDH1A1 (0.42) ALDH1A1MAPK1TSHRHSD17B10CASP1
SCHEMBL30040588 0.84 ALDH1A1 (0.42) ALDH1A1MAPK1TSHRHSD17B10CASP1
SCHEMBL13002341 0.84 ALDH1A1 (0.42) ALDH1A1MAPK1TSHRHSD17B10CASP1
SCHEMBL16859291 0.83 ALDH1A1 (0.44) ALDH1A1MAPK1TSHRHSD17B10CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115461329-B Compound and organic light-emitting element comprising same 株式会社LG化学 2024-07-23 CN disclosed
CN-115461329-A Compound and organic light-emitting element comprising same 株式会社LG化学 2022-12-09 CN disclosed