SCHEMBL30104142

SCHEMBL30104142

c1ncc2c(n1)CCS2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL589910 1.00
SCHEMBL30708579 0.88
SCHEMBL31712906 0.67
SCHEMBL30870718 0.67 TNKS2 (0.46)
SCHEMBL9537255 0.67 TNKS2 (0.46)
SCHEMBL5760552 0.65 MEN1 (0.36)
SCHEMBL4455107 0.65
SCHEMBL218247 0.64
SCHEMBL7196077 0.63 TNKS2 (0.36)
SCHEMBL9536810 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070278-A Bifunctional protein degradation agent containing aryl substituted heteroaryl and application thereof 标新生物医药科技(上海)有限公司 2026-05-19 CN claimed
CN-119613402-A Polysubstituted aromatic nitrogen heterocyclic compound, preparation method and application thereof 复旦大学 2025-03-14 CN claimed
CN-115417825-A Five-membered or six-membered fused ring pyrimidine cyclopropyl naphthalene derivative and preparation method and application thereof 山东大学 2022-12-02 CN claimed
CN-122070278-A Bifunctional protein degradation agent containing aryl substituted heteroaryl and application thereof 标新生物医药科技(上海)有限公司 2026-05-19 CN disclosed
CN-116925099-B Preparation method and application of chiral dihydrothienopyrimidine sulfoxide and 2-and 4-substituted compound thereof 厦门大学 2025-06-03 CN disclosed
CN-119613402-A Polysubstituted aromatic nitrogen heterocyclic compound, preparation method and application thereof 复旦大学 2025-03-14 CN disclosed
CN-115417825-B Five-membered or six-membered fused ring pyrimidine cyclopropyl naphthalene derivative and preparation method and application thereof 山东大学 2024-06-28 CN disclosed
CN-116925099-A Preparation method and application of chiral dihydrothienopyrimidine sulfoxide and 2-and 4-substituted compound thereof 厦门大学 2023-10-24 CN disclosed
CN-115417825-A Five-membered or six-membered fused ring pyrimidine cyclopropyl naphthalene derivative and preparation method and application thereof 山东大学 2022-12-02 CN disclosed