SCHEMBL9536810

SCHEMBL9536810

c1ncc2c(n1)CC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29438246 0.85
SCHEMBL29460883 0.85 SIGMAR1 (0.43)
SCHEMBL19450091 0.83 SIGMAR1 (0.41)
SCHEMBL3987657 0.83 SIGMAR1 (0.41)
SCHEMBL19450166 0.83 SIGMAR1 (0.41)
SCHEMBL2342848 0.80 CHRNB2 (0.48)
SCHEMBL30028826 0.78 CYP2A6 (0.38)
Hydrochloric Acid SCHEMBL6438259 0.78 CHRNB2 (0.47)
SCHEMBL19450272 0.77
SCHEMBL19450129 0.75 SIGMAR1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4397661-A1 COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2024-07-10 EP disclosed
EP-4269399-A1 FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF Sichuan Haisco Pharmaceutical Co., Ltd. (CN) 2023-11-01 EP disclosed
WO-2023109892-A1 COMPOUND FOR INHIBITING OR DEGRADING BRD9, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF 海思科医药集团股份有限公司 2023-06-22 WO disclosed
WO-2023016518-A1 HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF 四川海思科制药有限公司 2023-02-16 WO disclosed
WO-2022223022-A1 FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL APPLICATION THEREOF 四川海思科制药有限公司 2022-10-27 WO disclosed
WO-2022135572-A1 FIVE-MEMBERED RING DERIVATIVE AND MEDICAL USE THEREOF 四川海思科制药有限公司 2022-06-30 WO disclosed
WO-2022111526-A1 BENZENE RING DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF 四川海思科制药有限公司 2022-06-02 WO disclosed
WO-2022002118-A1 FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL USE THEREOF 四川海思科制药有限公司 2022-01-06 WO disclosed
US-20180212180-A1 POLYMERIC CHARGE TRANSFER LAYER AND ORGANIC ELECTRONIC DEVICE CONTAINING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2018-07-26 US disclosed
WO-2017031622-A1 POLYMERIC CHARGE TRANSFER LAYER AND ORGANIC ELECTRONIC DEVICE CONTAINING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2017-03-02 WO disclosed
WO-2014202027-A1 SPIROCYCLIC DERIVATIVE OF 4,5-DIHYDROPYRAZOLO[3,4-C]PYRIDINE-2-ONE, PREPARATION METHOD AND USE THEREOF 四川海思科制药有限公司 (CN) 2014-12-24 WO disclosed
EP-0337944-B1 UREAS CIBA-GEIGY AG (CH) 1993-07-28 EP disclosed
EP-0337944-A1 Ureas CIBA-GEIGY AG (CH) 1989-10-18 EP disclosed