Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 10/20 | 0.58 |
| ▸ | PDE4A | P27815 | 9/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29483452 | 0.85 | PDE4B (0.71) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL11554004 | 0.85 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL4996892 | 0.82 | RECQL (0.67) | CYP1A2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11549697 | 0.82 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL4996875 | 0.82 | RECQL (0.67) | CYP1A2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12507433 | 0.82 | RECQL (0.67) | CYP1A2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8638085 | 0.81 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL8638441 | 0.81 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL11758912 | 0.81 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL8359619 | 0.80 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4DCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110333-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2023-01-04 | — | — | EP | disclosed |