Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 10/20 | 0.58 |
| ▸ | PDE4A | P27815 | 9/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549424 | 0.83 | TUBB4A (0.57) | PDE4BPDE4APDE4CPDE4DTUBB4A | |
| SCHEMBL30104252 | 0.82 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL11554004 | 0.81 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL29483452 | 0.81 | PDE4B (0.71) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL8638085 | 0.80 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL8638441 | 0.80 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL11758912 | 0.80 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL4995254 | 0.80 | TUBB4A (0.58) | PDE4BTSHRALDH1A1TUBB4ATUBB | |
| SCHEMBL4995246 | 0.80 | TUBB4A (0.58) | PDE4BTSHRALDH1A1TUBB4ATUBB | |
| SCHEMBL8359619 | 0.79 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4DCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172090-A | FROM ISOAZOLE AND BENZALDEHYDE | BASF AKTIENGESELLSCHAFT (DE) | 1979-10-23 | — | — | US | disclosed |