⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16699003 | 0.94 | — | — | |
| SCHEMBL30104255 | 0.93 | — | — | |
| SCHEMBL19778894 | 0.86 | CYP3A4 (0.30) | — | |
| SCHEMBL16699605 | 0.86 | SLC6A1 (0.30) | — | |
| SCHEMBL19778896 | 0.85 | CYP3A4 (0.30) | — | |
| SCHEMBL29788385 | 0.82 | — | — | |
| SCHEMBL16710859 | 0.80 | NPSR1 (0.32) | — | |
| SCHEMBL16710444 | 0.80 | NPSR1 (0.32) | — | |
| SCHEMBL16698697 | 0.80 | — | — | |
| SCHEMBL19778893 | 0.79 | EGLN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250236623-A1 | PYRROLO[1,2-f][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES, INC. | 2025-07-24 | — | — | US | disclosed |
| EP-4122932-A1 | PYRROLO[1,2-F][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | Gilead Sciences, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |