Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29153696 | 0.84 | CCR9 (0.38) | POLBMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL24640542 | 0.83 | POLB (0.47) | POLBSMN1; SMN2MAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL31491281 | 0.83 | POLB (0.46) | POLBSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL833013 | 0.81 | NOD2 (0.50) | POLBSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL2545450 | 0.80 | NOD2 (0.44) | POLBSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL926599 | 0.79 | POLB (0.41) | POLBSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL1093477 | 0.78 | MAPT (0.46) | POLBSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL24640541 | 0.77 | POLB (0.41) | POLBSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL30882745 | 0.76 | NOD2 (0.39) | POLBSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL832224 | 0.76 | NOD2 (0.41) | POLBSMN1; SMN2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430606-A | Sulfonamide PARP7 inhibitors | 山东轩竹医药科技有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022247839-A1 | PARP7 INHIBITOR | 山东轩竹医药科技有限公司 | 2022-12-01 | — | — | WO | disclosed |