Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832297 | 1.00 | ACSS2 (0.67) | ACSS2 | |
| SCHEMBL25368529 | 0.82 | ACSS2 (0.67) | ACSS2 | |
| SCHEMBL25366507 | 0.82 | ACSS2 (0.67) | ACSS2 | |
| SCHEMBL23843413 | 0.82 | ACSS2 (0.67) | ACSS2 | |
| SCHEMBL23832298 | 0.82 | ACSS2 (0.80) | ACSS2 | |
| SCHEMBL25365697 | 0.82 | ACSS2 (0.67) | ACSS2 | |
| SCHEMBL23832149 | 0.82 | ACSS2 (0.61) | ACSS2 | |
| SCHEMBL30059929 | 0.82 | ACSS2 (0.61) | ACSS2 | |
| SCHEMBL25367705 | 0.81 | ACSS2 (1.00) | ACSS2 | |
| SCHEMBL23843578 | 0.81 | ACSS2 (0.78) | ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121429-A1 | CONDENSED PYRIDINE DERIVASTIVES SUBSTITUED BY AMIDE FUNCTIONS AS ACSS2 INHIBITORS | Merck Patent GmbH (DE) | 2023-01-25 | — | — | EP | disclosed |
| CN-115443275-A | Condensed pyridine derivatives substituted with amide functions as ACSS2 inhibitors | 默克专利股份公司 | 2022-12-06 | — | — | CN | disclosed |