Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831600 | 1.00 | RAB9A (0.54) | RAB9AHTTALDH1A1PTGER3MAPT | |
| SCHEMBL23831925 | 0.92 | RAB9A (0.52) | RAB9AHTTALDH1A1PTGER3MAPT | |
| SCHEMBL30105235 | 0.92 | RAB9A (0.52) | RAB9AHTTALDH1A1PTGER3MAPT | |
| SCHEMBL30105262 | 0.88 | RAB9A (0.49) | RAB9AHTTALDH1A1PTGER3MAPT | |
| SCHEMBL23831951 | 0.88 | RAB9A (0.49) | RAB9AHTTALDH1A1PTGER3MAPT | |
| SCHEMBL23831909 | 0.88 | RAB9A (0.42) | RAB9AHTTALDH1A1MAPTMEN1 | |
| SCHEMBL30105062 | 0.88 | RAB9A (0.42) | RAB9AHTTALDH1A1MAPTMEN1 | |
| SCHEMBL23832055 | 0.88 | HTT (0.42) | RAB9AHTTALDH1A1MAPTMEN1 | |
| SCHEMBL30104999 | 0.88 | HTT (0.42) | RAB9AHTTALDH1A1MAPTMEN1 | |
| SCHEMBL23831658 | 0.87 | PTGER3 (0.48) | RAB9AHTTALDH1A1PTGER3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |