Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | VSIG8 | P0DPA2 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | MARS1 | P56192 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831902 | 1.00 | MAPT (0.54) | MAPTPKMHTTGRIK1KMT2A | |
| SCHEMBL30105314 | 0.91 | MAPT (0.52) | MAPTPKMHTTGRIK1KMT2A | |
| SCHEMBL30105022 | 0.91 | MAPT (0.52) | MAPTPKMHTTGRIK1KMT2A | |
| SCHEMBL23832101 | 0.91 | MAPT (0.52) | MAPTPKMHTTGRIK1KMT2A | |
| SCHEMBL23831730 | 0.91 | MAPT (0.52) | MAPTPKMHTTGRIK1KMT2A | |
| SCHEMBL23831994 | 0.90 | LMNA (0.44) | MAPTPKMHTTGRIK1KMT2A | |
| SCHEMBL30104939 | 0.90 | LMNA (0.44) | MAPTPKMHTTGRIK1KMT2A | |
| SCHEMBL23831985 | 0.90 | MAPT (0.51) | MAPTPKMHTTGRIK1KMT2A | |
| SCHEMBL23831786 | 0.90 | GRIK1 (0.52) | MAPTPKMHTTGRIK1KMT2A | |
| SCHEMBL30105316 | 0.90 | GRIK1 (0.52) | MAPTPKMHTTGRIK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |