Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 5/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832028 | 1.00 | AR (0.43) | ARKMT2ASMARCA2SMARCA4NPC1 | |
| SCHEMBL30105015 | 0.88 | SMARCA2 (0.54) | KMT2ASMARCA2SMARCA4NPC1RAB9A | |
| SCHEMBL30105307 | 0.88 | KCNH2 (0.39) | KMT2ASMARCA2SMARCA4NPC1RAB9A | |
| SCHEMBL23831929 | 0.88 | SMARCA2 (0.54) | KMT2ASMARCA2SMARCA4NPC1RAB9A | |
| SCHEMBL23832005 | 0.88 | KCNH2 (0.39) | KMT2ASMARCA2SMARCA4NPC1RAB9A | |
| SCHEMBL23831972 | 0.87 | CNR1 (0.43) | KMT2ANPC1RAB9ASMN1; SMN2KDR | |
| SCHEMBL30105096 | 0.87 | CNR1 (0.43) | KMT2ANPC1RAB9ASMN1; SMN2KDR | |
| SCHEMBL23832066 | 0.85 | AR (0.45) | ARKMT2ASMARCA2SMARCA4NPC1 | |
| SCHEMBL23832090 | 0.81 | ACP1 (0.41) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL30105054 | 0.81 | ACP1 (0.41) | KMT2ANPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |