Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831972 | 1.00 | CNR1 (0.43) | CNR1KCNK3KCNK9RAB9AALDH1A1 | |
| SCHEMBL23832028 | 0.87 | AR (0.43) | RAB9AHTTMEN1KMT2AKDR | |
| SCHEMBL30105294 | 0.87 | AR (0.43) | RAB9AHTTMEN1KMT2AKDR | |
| SCHEMBL30105050 | 0.87 | RAB9A (0.50) | CNR1KCNK3KCNK9RAB9AALDH1A1 | |
| SCHEMBL23831910 | 0.87 | RAB9A (0.50) | CNR1KCNK3KCNK9RAB9AALDH1A1 | |
| SCHEMBL23831637 | 0.83 | CNR1 (0.43) | CNR1KCNK3KCNK9RAB9AALDH1A1 | |
| SCHEMBL30105307 | 0.83 | KCNH2 (0.39) | RAB9AALDH1A1HTTMEN1KMT2A | |
| SCHEMBL23831929 | 0.83 | SMARCA2 (0.54) | CNR1RAB9AHTTMEN1KMT2A | |
| SCHEMBL23832005 | 0.83 | KCNH2 (0.39) | RAB9AALDH1A1HTTMEN1KMT2A | |
| SCHEMBL30105015 | 0.83 | SMARCA2 (0.54) | CNR1RAB9AHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |