Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23831878 | 1.00 | EPHX2 (0.40) | EPHX2P2RY1HTTTRPV1NPC1 | |
| SCHEMBL23831992 | 0.93 | EPHX2 (0.40) | EPHX2P2RY1HTTNPC1POLB | |
| SCHEMBL30105204 | 0.93 | EPHX2 (0.40) | EPHX2P2RY1HTTNPC1POLB | |
| SCHEMBL30105311 | 0.89 | KDR (0.44) | EPHX2P2RY1TRPV1NPC1RAB9A | |
| SCHEMBL23831767 | 0.89 | KDR (0.44) | EPHX2P2RY1TRPV1NPC1RAB9A | |
| SCHEMBL30104999 | 0.89 | HTT (0.42) | EPHX2P2RY1HTTTRPV1RAB9A | |
| SCHEMBL23832055 | 0.89 | HTT (0.42) | EPHX2P2RY1HTTTRPV1RAB9A | |
| SCHEMBL23831874 | 0.88 | HTT (0.43) | EPHX2P2RY1HTTNPC1POLB | |
| SCHEMBL30104962 | 0.88 | HTT (0.43) | EPHX2P2RY1HTTNPC1POLB | |
| SCHEMBL23831951 | 0.87 | RAB9A (0.49) | HTTNPC1RAB9ASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |