Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 13/20 | 0.59 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.57 |
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BMP1 | P13497 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2445958 | 0.79 | TAS2R14 (0.82) | TAS2R14CXCR3PTGESTAS2R8CNR1 | |
| SCHEMBL28729777 | 0.79 | TAS2R14 (0.80) | TAS2R14CXCR3PTGESTAS2R8CNR1 | |
| SCHEMBL23878154 | 0.78 | MAPT (0.61) | TAS2R14CXCR3PTGESTAS2R8CNR1 | |
| SCHEMBL19284831 | 0.75 | CNR2 (0.62) | TAS2R14CXCR3PTGESTAS2R8CNR1 | |
| SCHEMBL1279440 | 0.74 | TAS2R14 (1.00) | TAS2R14CXCR3PTGESTAS2R8CNR1 | |
| SCHEMBL22175661 | 0.73 | TAS2R14 (0.77) | TAS2R14CXCR3PTGESTAS2R8CNR1 | |
| SCHEMBL1279080 | 0.72 | TAS2R14 (0.77) | TAS2R14CXCR3PTGESTAS2R8CNR1 | |
| SCHEMBL1278846 | 0.72 | TAS2R14 (1.00) | TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL1169926 | 0.72 | TAS2R14 (1.00) | TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL12260294 | 0.71 | TAS2R14 (0.72) | TAS2R14CXCR3PTGESTAS2R8CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111377917-B | Heterocyclic compound, intermediate, preparation method and application thereof | 武汉朗来科技发展有限公司 | 2022-12-06 | — | — | CN | disclosed |