Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.41 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL878052 | 1.00 | TDP1 (0.64) | TDP1APPMAPTGAAP2RX7 | |
| SCHEMBL7529401 | 0.85 | TDP1 (0.66) | TDP1MAPTGAAP2RX7HTR1A | |
| SCHEMBL12748233 | 0.83 | TDP1 (0.64) | TDP1MAPTGAAP2RX7HTR1A | |
| SCHEMBL21635515 | 0.81 | TDP1 (0.60) | TDP1MAPTGAAP2RX7HDAC1 | |
| SCHEMBL9762866 | 0.77 | TDP1 (0.64) | TDP1P2RX7HTR1AADRA1DADRA1A | |
| SCHEMBL1581284 | 0.76 | ACP1 (0.53) | TDP1MAPTMEN1KMT2A | |
| Bromide SCHEMBL20984474 | 0.75 | TDP1 (0.54) | TDP1MAPTGAAP2RX7HDAC1 | |
| SCHEMBL9227792 | 0.74 | TDP1 (0.53) | TDP1MAPTGAAP2RX7HDAC1 | |
| SCHEMBL15764263 | 0.74 | TDP1 (0.53) | TDP1MAPTGAAP2RX7HDAC1 | |
| SCHEMBL5511518 | 0.74 | TDP1 (0.57) | TDP1MAPTP2RX7HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229093-B | Carbazole compounds for in vivo imaging | 通用电气健康护理有限公司 | 2022-12-13 | — | — | CN | disclosed |