Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795123 | 0.80 | MEN1 (0.49) | TDP1HTR1AALDH1A1RAB9A | |
| SCHEMBL7529401 | 0.79 | TDP1 (0.66) | TDP1P2RX7HTR1AADRA1DADRA1A | |
| SCHEMBL30106110 | 0.77 | TDP1 (0.64) | TDP1P2RX7HTR1AADRA1DADRA1A | |
| SCHEMBL12748233 | 0.77 | TDP1 (0.64) | TDP1P2RX7HTR1AADRA1DADRA1A | |
| SCHEMBL878052 | 0.77 | TDP1 (0.64) | TDP1P2RX7HTR1AADRA1DADRA1A | |
| Sulfuric Acid SCHEMBL20984891 | 0.76 | TDP1 (0.51) | TDP1P2RX7HCRTR1HCRTR2HDAC1 | |
| SCHEMBL21635515 | 0.75 | TDP1 (0.60) | TDP1P2RX7HDAC1HDAC8HDAC6 | |
| SCHEMBL10799697 | 0.75 | MEN1 (0.46) | TDP1MAPK1RAB9A | |
| SCHEMBL10798749 | 0.74 | MEN1 (0.55) | ALDH1A1MAPK1NPSR1 | |
| SCHEMBL10797282 | 0.73 | KMT2A (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003052-A | Monoazo fiber reactive dye for cellulose, polyamides, wool, silk, polyurethanes and leather | CIBA-GEIGY CORPORATION (US) | 1991-03-26 | — | — | US | disclosed |
| US-4652634-A | Water-soluble monoazo compounds containing a N-(sulfoalkyl)-aniline coupling component and a fiber-reactive group of the vinylsulfonyl series in the phenyl or benzothiazole diazo component, suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| EP-0051808-B1 | WATER-SOLUBLE MONOAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-04 | — | — | EP | disclosed |
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |