SCHEMBL30106217

SCHEMBL30106217

Fc1c(F)c(Cl)c2cc3ccccc3cc2c1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.38
CYP1A2 P05177 2/20 0.38
MAPT P10636 1/20 0.36
ALDH1A1 P00352 2/20 0.34
HIF1A Q16665 1/20 0.34
CYP1B1 Q16678 1/20 0.34
HSD17B10 Q99714 1/20 0.34
NQO1 P15559 1/20 0.34
SOD1 P00441 1/20 0.33
HPRT1 P00492 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
TRPM4 Q8TD43 1/20 0.31
ESR1 P03372 3/20 0.31
ESR2 Q92731 3/20 0.31
NQO2 P16083 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
MEN1 O00255 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6837157 0.86 CYP2A6 (0.48) CYP2A6CYP1A2ALDH1A1HIF1ACYP1B1
SCHEMBL2790386 0.81 CYP2A6 (0.44) CYP2A6CYP1A2MAPTALDH1A1HIF1A
SCHEMBL8916693 0.81 CYP2A6 (0.44) CYP2A6CYP1A2MAPTALDH1A1HIF1A
SCHEMBL31518688 0.78 CYP2A6 (0.50) CYP2A6CYP1A2MAPTALDH1A1HIF1A
SCHEMBL15757917 0.78 CYP2A6 (0.50) CYP2A6CYP1A2MAPTALDH1A1HIF1A
SCHEMBL4839059 0.78 CYP2A6 (0.50) CYP2A6CYP1A2ALDH1A1HIF1ACYP1B1
SCHEMBL7918983 0.76 CYP2A6 (0.48) CYP2A6CYP1A2MAPTALDH1A1HIF1A
SCHEMBL18606148 0.76 CYP2A6 (0.39) CYP2A6CYP1A2ALDH1A1HIF1ACYP1B1
SCHEMBL18606189 0.75 CYP2A6 (0.42) CYP2A6CYP1A2ALDH1A1HIF1ACYP1B1
SCHEMBL30843834 0.74 MAOA (0.50) CYP2A6CYP1A2MAPTALDH1A1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111721856-B Method for detecting pyrethroid pesticide metabolite in tea 中国农业科学院茶叶研究所 2022-12-13 CN disclosed