SCHEMBL30106264

SCHEMBL30106264

CCOC(=O)c1nc(-c2ccc(C(C)(C)C)cc2)oc1-c1ccccc1[N+](=O)[O-]

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TARBP2 Q15633 7/20 0.49
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 2/20 0.45
HPGD P15428 1/20 0.45
KMT2A Q03164 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PDCD4 Q53EL6 1/20 0.43
IKBKB O14920 2/20 0.42
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
DHODH Q02127 1/20 0.38
GAA P10253 2/20 0.37
HRH2 P25021 1/20 0.37
HRH1 P35367 1/20 0.37
SLC5A1 P13866 1/20 0.37
SLC5A2 P31639 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TRPV1 Q8NER1 1/20 0.37
EIF4E P06730 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7695771 1.00 TARBP2 (0.49) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL21541929 0.91 TARBP2 (0.48) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL30740876 0.91 TARBP2 (0.48) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL29158993 0.90 TARBP2 (0.61) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL20361981 0.90 TARBP2 (0.58) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL29158785 0.89 TARBP2 (0.52) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL30740865 0.88 TARBP2 (0.59) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL21541935 0.88 TARBP2 (0.59) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL29158670 0.88 TARBP2 (0.51) TARBP2ALDH1A1KDM4EHPGDKMT2A
SCHEMBL21541932 0.87 TARBP2 (0.60) TARBP2ALDH1A1KDM4EHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117396465-A Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same 阿斯克里斯有限公司 2024-01-12 CN claimed
WO-2022255764-A1 NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE 주식회사 에즈큐리스 2022-12-08 WO claimed
CN-117396465-A Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same 阿斯克里斯有限公司 2024-01-12 CN disclosed
WO-2022255764-A1 NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE 주식회사 에즈큐리스 2022-12-08 WO disclosed