Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TARBP2 | Q15633 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158993 | 0.98 | TARBP2 (0.61) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL29158785 | 0.93 | TARBP2 (0.52) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL21541935 | 0.92 | TARBP2 (0.59) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL30740865 | 0.92 | TARBP2 (0.59) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL29158670 | 0.92 | TARBP2 (0.51) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL21541932 | 0.91 | TARBP2 (0.60) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL30740866 | 0.91 | TARBP2 (0.60) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL29158733 | 0.90 | KDM4E (0.53) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL30106264 | 0.90 | TARBP2 (0.49) | TARBP2ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL29158571 | 0.90 | TARBP2 (0.49) | TARBP2ALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11168094-B2 | Quinolinone derivative and pharmaceutical composition for preventing or treating allergic diseases such as asthma or atopic dermatitis including the quinolinone derivative as active ingredient | AZCURIS CO., LTD. (KR) | 2021-11-09 | — | — | US | disclosed |
| US-20200140457-A1 | NOVEL QUINOLINONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ALLERGIC DISEASES SUCH AS ASTHMA OR ATOPIC DERMATITIS INCLUDING THE QUINOLINONE DERIVATIVE AS ACTIVE INGREDIENT | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) | 2020-05-07 | — | — | US | disclosed |
| EP-3567044-A1 | NOVEL QUINOLINONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ALLERGIC DISEASE SUCH AS ASTHMA OR ATOPY COMPRISING SAME AS ACTIVE INGREDIENT | Korea University Research and Business Foundation, Sejong Campus (KR) | 2019-11-13 | — | — | EP | disclosed |
| WO-2018128407-A1 | NOVEL QUINOLINONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ALLERGIC DISEASE SUCH AS ASTHMA OR ATOPY COMPRISING SAME AS ACTIVE INGREDIENT | 고려대학교 세종산학협력단 | 2018-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168094-B2 | Quinolinone derivative and pharmaceutical composition for preventing or treating allergic diseases such as asthma or atopic dermatitis including the quinolinone derivative as active ingredient | TSLP, IL33, IL5 | TARBP2 3669/4885ALDH1A1 1899/4885KDM4E 3092/4885 |
| US-20200140457-A1 | NOVEL QUINOLINONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ALLERGIC DISEASES SUCH AS ASTHMA OR ATOPIC DERMATITIS INCLUDING THE QUINOLINONE DERIVATIVE AS ACTIVE INGREDIENT | TSLP, IL33, TMEM33 | TARBP2 3633/4885ALDH1A1 1038/4885KDM4E 3166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.