Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 2/20 | 0.40 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30106679 | 0.85 | TBXAS1 (0.61) | TBXAS1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL30106674 | 0.83 | TBXAS1 (0.62) | TBXAS1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL30106673 | 0.83 | TBXAS1 (0.62) | TBXAS1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL30106700 | 0.81 | TBXAS1 (0.62) | TBXAS1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL30106659 | 0.81 | TBXAS1 (0.59) | TBXAS1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL12834662 | 0.80 | TBXAS1 (0.57) | TBXAS1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL31127499 | 0.80 | TBXAS1 (0.58) | TBXAS1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL30106634 | 0.79 | TBXAS1 (0.61) | TBXAS1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL30106651 | 0.77 | TBXAS1 (0.58) | TBXAS1ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL12761935 | 0.77 | TBXAS1 (0.60) | TBXAS1ALDH1A1LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279184-A1 | HETEROAROMATIC ANALOGUES OF 3-BENZYLMENADIONE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | UNIVERSITE DE HAUTE ALSACE (FR) | 2024-08-22 | — | — | US | disclosed |
| EP-4347566-A1 | HETEROAROMATIC ANALOGUES OF 3-BENZYLMENADIONE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | Centre National de la Recherche Scientifique (FR) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022254034-A1 | HETEROAROMATIC ANALOGUES OF 3-BENZYLMENADIONE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2022-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279184-A1 | HETEROAROMATIC ANALOGUES OF 3-BENZYLMENADIONE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CYP1B1, CYP1A1, CYP2B6 | TBXAS1 415/4885ALDH1A1 524/4885LMNA 850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.