Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21690442 | 1.00 | MEN1 (0.51) | MEN1KMT2AGAAPOLBTDP1 | |
| SCHEMBL26793178 | 1.00 | MEN1 (0.51) | MEN1KMT2AGAAPOLBTDP1 | |
| SCHEMBL12154974 | 0.91 | SLC7A5 (0.54) | MEN1KMT2ATDP1SLC7A5PTGS1 | |
| SCHEMBL1733848 | 0.91 | SLC7A5 (0.54) | MEN1KMT2ATDP1SLC7A5PTGS1 | |
| SCHEMBL31370415 | 0.91 | SLC7A5 (0.54) | MEN1KMT2ATDP1SLC7A5PTGS1 | |
| SCHEMBL17189671 | 0.90 | KMT2A (0.51) | MEN1KMT2AGAAPOLBTDP1 | |
| SCHEMBL6714833 | 0.77 | LMNA (0.56) | GAAPOLBTDP1SLC7A5PTGS1 | |
| Tyrosine SCHEMBL28042203 | 0.77 | SLC7A5 (0.60) | MEN1KMT2AGAAPOLBTDP1 | |
| Water SCHEMBL11335239 | 0.76 | LMNA (0.55) | GAAPOLBTDP1SLC7A5PTGS1 | |
| SCHEMBL11603982 | 0.75 | GRIA2 (0.61) | GAATDP1SLC7A5PTGS1ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373983-A2 | A PROTEIN-BASED SENSOR FOR METALS IN ENVIRONMENTAL SAMPLES AND USES THEREOF | The Penn State Research Foundation (US) | 2024-05-29 | — | — | EP | disclosed |
| WO-2023004333-A2 | A PROTEIN-BASED SENSOR FOR METALS IN ENVIRONMENTAL SAMPLES AND USES THEREOF | THE PENN STATE RESEARCH FOUNDATION (US) | 2023-01-26 | — | — | WO | disclosed |