Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY1 | Q08828 | 16/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.77 |
| ▸ | GMNN | O75496 | 1/20 | 0.77 |
| ▸ | BLM | P54132 | 1/20 | 0.77 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.77 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.77 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.77 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.77 |
| ▸ | HTR1A | P08908 | 1/20 | 0.77 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.77 |
| ▸ | HTR2A | P28223 | 1/20 | 0.77 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.77 |
| ▸ | SCN1A | P35498 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10920909 | 1.00 | ADCY1 (0.77) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| SCHEMBL3130497 | 1.00 | ADCY1 (0.77) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| SCHEMBL11538367 | 1.00 | ADCY1 (0.77) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| SCHEMBL10921843 | 1.00 | ADCY1 (0.77) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| SCHEMBL10495012 | 0.93 | ADCY1 (0.68) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| SCHEMBL9737363 | 0.93 | ADCY1 (0.68) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| Colforsin SCHEMBL23750589 | 0.87 | ADCY1 (1.00) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| Colforsin SCHEMBL4917705 | 0.87 | ADCY1 (1.00) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| Colforsin SCHEMBL21530309 | 0.87 | ADCY1 (1.00) | ADCY1MAPK1CYP3A4TSHRSLC2A1 | |
| Colforsin SCHEMBL14614874 | 0.87 | ADCY1 (1.00) | ADCY1MAPK1CYP3A4TSHRSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586217-B | Preparation method of forskolin based on domestic coleus forskohlii | 云南省药物研究所 | 2024-03-19 | — | — | CN | claimed |
| CN-117586217-A | Preparation method of fossa Lin Gaoxiao based on domestic coleus forskohlii | 云南省药物研究所 | 2024-02-23 | — | — | CN | claimed |
| CN-115414348-A | Application of forskolin and derivatives thereof in preparation of medicine for treating psoriasis | 昆明医科大学 | 2022-12-02 | — | — | CN | claimed |
| CN-117586217-B | Preparation method of forskolin based on domestic coleus forskohlii | 云南省药物研究所 | 2024-03-19 | — | — | CN | disclosed |
| CN-117586217-A | Preparation method of fossa Lin Gaoxiao based on domestic coleus forskohlii | 云南省药物研究所 | 2024-02-23 | — | — | CN | disclosed |
| US-20230346956-A1 | COMPLEX OF 7-DEACETYLFORSKOLIN AND PVP | SciPharm S.à.r.l (LU) | 2023-11-02 | — | — | US | disclosed |
| CN-115414348-A | Application of forskolin and derivatives thereof in preparation of medicine for treating psoriasis | 昆明医科大学 | 2022-12-02 | — | — | CN | disclosed |
| CN-115414348-A | Application of forskolin and derivatives thereof in preparation of medicine for treating psoriasis | 昆明医科大学 | 2022-12-02 | — | — | CN | disclosed |