SCHEMBL30108346

SCHEMBL30108346

C[C@@H](O)[C@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 17/20 0.59
▸ SCTR P47872 1/20 0.59
▸ GCGR P47871 1/20 0.56
▸ CALCR P30988 2/20 0.54
▸ F2 P00734 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30207768 0.97 GLP1R (0.56) GLP1RSCTRGCGRCALCR
SCHEMBL30320200 0.97 GLP1R (0.56) GLP1RSCTRGCGRCALCR
SCHEMBL30320225 0.97 GLP1R (0.56) GLP1RSCTRGCGRCALCR
SCHEMBL29913342 0.97 GLP1R (0.56) GLP1RSCTRGCGRCALCR
SCHEMBL30320221 0.97 GLP1R (0.56) GLP1RSCTRGCGRCALCR
SCHEMBL30320255 0.96 GLP1R (0.55) GLP1RSCTRGCGR
SCHEMBL29367449 0.96 GLP1R (0.58) GLP1RSCTRGCGRCALCR
SCHEMBL29364498 0.96 GLP1R (0.58) GLP1RSCTRGCGRCALCR
SCHEMBL29367867 0.96 GLP1R (0.58) GLP1RSCTRGCGRCALCR
SCHEMBL30637756 0.95 GLP1R (0.57) GLP1RSCTRF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277816-A1 POLYPEPTIDE CONJUGATE AND APPLICATION THEREOF IN PREPARATION OF DRUG FOR TREATING DISEASES RELATED TO GLUCOSE METABOLISM PEGBIO CO., LTD. (CN) 2024-08-22 — — US claimed
WO-2023001186-A1 POLYPEPTIDE CONJUGATE AND APPLICATION THEREOF IN PREPARATION OF DRUG FOR TREATING DISEASES RELATED TO GLUCOSE METABOLISM 派格生物医药(苏州)股份有限公司 2023-01-26 — — WO claimed
CN-115634285-A Application of polypeptide conjugate in preparation of medicines for treating diseases related to glycometabolism 派格生物医药(苏州)股份有限公司 2023-01-24 — — CN claimed
US-20240277816-A1 POLYPEPTIDE CONJUGATE AND APPLICATION THEREOF IN PREPARATION OF DRUG FOR TREATING DISEASES RELATED TO GLUCOSE METABOLISM PEGBIO CO., LTD. (CN) 2024-08-22 — — US disclosed
CN-118512602-A Compound pharmaceutical composition and application thereof 派格生物医药(苏州)股份有限公司 2024-08-20 — — CN disclosed
US-20230302093-A1 NASAL POWDER FORMULATION FOR TREATMENT OF HYPOGLYCEMIA AMPHASTAR PHARMACEUTICALS, INC. 2023-09-28 — — US disclosed
WO-2023001186-A1 POLYPEPTIDE CONJUGATE AND APPLICATION THEREOF IN PREPARATION OF DRUG FOR TREATING DISEASES RELATED TO GLUCOSE METABOLISM 派格生物医药(苏州)股份有限公司 2023-01-26 — — WO disclosed
CN-115634285-A Application of polypeptide conjugate in preparation of medicines for treating diseases related to glycometabolism 派格生物医药(苏州)股份有限公司 2023-01-24 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277816-A1 POLYPEPTIDE CONJUGATE AND APPLICATION THEREOF IN PREPARATION OF DRUG FOR TREATING DISEASES RELATED TO GLUCOSE METABOLISM IAPP, GIPR, GCG GLP1R 5/4885SCTR 58/4885GCGR 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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