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Sugi Predict / Compounds / SCHEMBL29367867

SCHEMBL29367867

SCHEMBL29367867

CC(C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](CO)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 15/20 0.58
▸ SCTR P47872 1/20 0.58
▸ GCGR P47871 1/20 0.55
▸ CALCR P30988 4/20 0.55
▸ CRHR1 P34998 1/20 0.53
▸ CRHR2 Q13324 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364498 1.00 GLP1R (0.58) GLP1RSCTRGCGRCALCRCRHR1
SCHEMBL29367449 1.00 GLP1R (0.58) GLP1RSCTRGCGRCALCRCRHR1
SCHEMBL29367002 1.00 GLP1R (0.58) GLP1RSCTRGCGRCALCRCRHR1
SCHEMBL30307617 0.96 GLP1R (0.64) GLP1RSCTRGCGR
SCHEMBL30108346 0.96 GLP1R (0.59) GLP1RSCTRGCGRCALCR
SCHEMBL29367013 0.94 GLP1R (0.66) GLP1RSCTR
SCHEMBL29364504 0.94 GLP1R (0.66) GLP1RSCTR
SCHEMBL30320225 0.93 GLP1R (0.56) GLP1RSCTRGCGRCALCR
SCHEMBL30320221 0.93 GLP1R (0.56) GLP1RSCTRGCGRCALCR
SCHEMBL30320200 0.93 GLP1R (0.56) GLP1RSCTRGCGRCALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115819551-A GLP-1/glucagon/gastrin receptor triple agonist with site-specific modification and application thereof 南京赛诺生物制药有限公司 2023-03-21 — — CN claimed
WO-2022111370-A1 GLP-1/GLUCAGON RECEPTOR DUAL-AGONIST AND APPLICATION THEREOF 江苏师范大学 2022-06-02 — — WO claimed
CN-112409460-B GLP-1/glucagon receptor dual agonist and application thereof 江苏师范大学 2022-02-01 — — CN claimed
CN-114349828-B GLP-1/glucagon receptor dual agonist and application thereof 江苏师范大学 2023-12-08 — — CN disclosed
CN-115819551-A GLP-1/glucagon/gastrin receptor triple agonist with site-specific modification and application thereof 南京赛诺生物制药有限公司 2023-03-21 — — CN disclosed
WO-2022111370-A1 GLP-1/GLUCAGON RECEPTOR DUAL-AGONIST AND APPLICATION THEREOF 江苏师范大学 2022-06-02 — — WO disclosed
CN-114349828-A GLP-1/glucagon receptor dual agonist and application thereof 江苏师范大学 2022-04-15 — — CN disclosed
CN-112409460-B GLP-1/glucagon receptor dual agonist and application thereof 江苏师范大学 2022-02-01 — — CN disclosed
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