Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108438 | 1.00 | MAPT (0.36) | MAPTGPR119ACACB | |
| SCHEMBL29220578 | 0.90 | MAPT (0.38) | MAPT | |
| SCHEMBL29220577 | 0.90 | MAPT (0.38) | MAPT | |
| SCHEMBL30873189 | 0.86 | MAPT (0.40) | MAPT | |
| SCHEMBL28699292 | 0.81 | PARP1 (0.34) | ACACB | |
| SCHEMBL22718273 | 0.81 | PARP1 (0.34) | ACACB | |
| SCHEMBL29829859 | 0.77 | GAA (0.35) | ACACB | |
| SCHEMBL22746961 | 0.76 | HSD17B10 (0.38) | MAPT | |
| SCHEMBL24775047 | 0.74 | PARP1 (0.33) | ACACB | |
| SCHEMBL29454284 | 0.73 | MAPT (0.33) | MAPTACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279227-A1 | FUSED HETEROCYCLIC DERIVATIVES | JANSSEN BIOTECH, INC. | 2024-08-22 | — | — | US | disclosed |
| WO-2024114709-A1 | A CRYSTAL FORM OF A FUSED HETEROCYCLE DERIVATIVE COMPOUND | Janssen Sciences Ireland Unlimited Company (IE) | 2024-06-06 | — | — | WO | disclosed |
| CN-117881661-A | Condensed heterocyclic derivative | 杨森科学爱尔兰无限公司 | 2024-04-12 | — | — | CN | disclosed |
| EP-4347036-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022253255-A1 | FUSED HETEROCYCLIC DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2022-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279227-A1 | FUSED HETEROCYCLIC DERIVATIVES | HAVCR2, HCCS, GOT2 | MAPT 2596/4885GPR119 1933/4885ACACB 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.