SCHEMBL30109027

SCHEMBL30109027

NCCCC[C@H](NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H](N)CCCCN)C(=O)NCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 5/20 0.50
▸ PTGS1 P23219 1/20 0.48
▸ GSTK1 Q9Y2Q3 1/20 0.48
▸ MMP2 P08253 1/20 0.46
▸ GNAI3 P08754 1/20 0.46
▸ GNAO1 P09471 1/20 0.46
▸ GNAI1 P63096 1/20 0.46
▸ GLO1 Q04760 1/20 0.45
▸ GSR P00390 1/20 0.44
▸ SIRT6 Q8N6T7 1/20 0.42
▸ SIRT1 Q96EB6 1/20 0.42
▸ NMT2 O60551 1/20 0.42
▸ NMT1 P30419 1/20 0.42
▸ FOLH1 Q04609 1/20 0.41
▸ DPP8 Q6V1X1 1/20 0.40
▸ DPP9 Q86TI2 1/20 0.40
▸ DPP7 Q9UHL4 1/20 0.40
▸ NOD1 Q9Y239 1/20 0.39
▸ SLC6A5 Q9Y345 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30984644 1.00 TERT (0.50) TERTPTGS1GSTK1MMP2GNAI3
SCHEMBL29486323 1.00 TERT (0.50) TERTPTGS1GSTK1MMP2GNAI3
SCHEMBL18234163 0.91 NMT1 (0.51) TERTPTGS1GSTK1MMP2GLO1
SCHEMBL29369655 0.91 PTGS1 (0.54) TERTPTGS1GSTK1MMP2GNAI3
SCHEMBL23968643 0.91 PTGS1 (0.54) TERTPTGS1GSTK1MMP2GNAI3
SCHEMBL30064268 0.90 FOLH1 (0.48) TERTPTGS1GSTK1MMP2GLO1
SCHEMBL18234267 0.90 NMT1 (0.53) TERTPTGS1GSTK1GLO1NMT2
SCHEMBL29397470 0.90 GSR (0.47) TERTPTGS1GSTK1MMP2GNAI3
SCHEMBL29945241 0.90 TERT (0.46) TERTPTGS1GSTK1MMP2GNAI3
SCHEMBL29569342 0.89 PTGS1 (0.43) TERTPTGS1GSTK1MMP2GNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378288-B2 Multimeric bicyclic peptide ligands BICYCLETX LIMITED (GB) 2025-08-05 — — US disclosed
US-20230220008-A1 MULTIMERIC BICYCLIC PEPTIDE LIGANDS BICYCLETX LIMITED (GB) 2023-07-13 — — US disclosed
US-11542304-B2 Multimeric bicyclic peptide ligands BICYCLETX LIMITED 2023-01-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378288-B2 Multimeric bicyclic peptide ligands CD40, TNFSF11, TNFRSF9 TERT 2447/4885PTGS1 4264/4885GSTK1 1725/4885
US-11542304-B2 Multimeric bicyclic peptide ligands CD40, TNFSF11, TNFRSF9 TERT 2447/4885PTGS1 4264/4885GSTK1 1725/4885
US-20230220008-A1 MULTIMERIC BICYCLIC PEPTIDE LIGANDS CD40, TNFSF11, TNFRSF9 TERT 2447/4885PTGS1 4264/4885GSTK1 1725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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