Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.40 |
| ▸ | CCND1 | P24385 | 3/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6029602 | 0.81 | MTNR1A (0.36) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL17452813 | 0.80 | CYP1A2 (0.39) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL16982968 | 0.78 | CYP2A6 (0.40) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL20314839 | 0.77 | HTR2C (0.38) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL29792740 | 0.75 | KMT2A (0.40) | MTNR1AMTNR1BALDH1A1CYP1A2KDM4E | |
| SCHEMBL16401098 | 0.75 | KMT2A (0.40) | MTNR1AMTNR1BALDH1A1CYP1A2KDM4E | |
| SCHEMBL13957826 | 0.75 | MEN1 (0.50) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL12536131 | 0.75 | CDK4 (0.39) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL29083460 | 0.74 | CYP3A4 (0.40) | MTNR1AMTNR1BKDM4EMEN1KMT2A | |
| SCHEMBL24448706 | 0.73 | CYP3A4 (0.37) | CDK4CCND1CCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278698-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |