Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1564236 | 0.92 | BDKRB2 (0.70) | BDKRB2 | |
| SCHEMBL13145072 | 0.78 | BDKRB2 (0.70) | BDKRB2 | |
| SCHEMBL1563888 | 0.78 | BDKRB2 (1.00) | BDKRB2 | |
| SCHEMBL13145751 | 0.75 | BDKRB2 (0.74) | BDKRB2 | |
| SCHEMBL1565066 | 0.72 | BDKRB2 (0.88) | BDKRB2RORC | |
| SCHEMBL1563198 | 0.71 | BDKRB2 (0.84) | BDKRB2RORC | |
| SCHEMBL13145042 | 0.71 | BDKRB2 (0.84) | BDKRB2RORC | |
| SCHEMBL2937315 | 0.71 | MAPT (0.49) | — | |
| SCHEMBL13145059 | 0.71 | BDKRB2 (0.83) | BDKRB2RORC | |
| SCHEMBL1563002 | 0.70 | BDKRB2 (0.79) | BDKRB2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144897-A1 | 8-OXY-QUINOLINE DERIVATIVES AS BRADYKININ B2 RECEPTOR MODULATORS | Jerini AG (DE) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008116620-A1 | 8-OXY-QUINOLINE DERIVATIVES AS BRADYKININ B2 RECEPTOR MODULATORS | JERINI AG (DE) | 2008-10-02 | — | — | WO | disclosed |