SCHEMBL30110285

SCHEMBL30110285

COCCOc1ccc2cc(C(C)=O)c(=O)oc2c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 9/20 0.71
GAA P10253 3/20 0.71
ALDH1A1 P00352 3/20 0.71
HPGD P15428 2/20 0.71
HSD11B1 P28845 2/20 0.62
MAOA P21397 7/20 0.61
CA12 O43570 2/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
CA4 P22748 1/20 0.59
CA5A P35218 1/20 0.59
CA7 P43166 1/20 0.59
CA5B Q9Y2D0 1/20 0.59
SLC16A3 O15427 2/20 0.57
KDM4E B2RXH2 3/20 0.57
GLA P06280 2/20 0.57
MEN1 O00255 1/20 0.57
S1PR4 O95977 1/20 0.57
MAPT P10636 1/20 0.57
MIF P14174 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6418716 0.90 SLC16A3 (0.71) MAOBGAAALDH1A1HPGDMAOA
SCHEMBL6420525 0.89 MAOB (0.60) MAOBGAAALDH1A1HPGDMAOA
SCHEMBL6420522 0.89 MAOB (0.60) MAOBGAAALDH1A1HPGDMAOA
SCHEMBL31206473 0.89 MAOB (0.60) MAOBGAAALDH1A1HPGDMAOA
SCHEMBL16674827 0.88 MAOB (0.69) MAOBGAAALDH1A1HPGDHSD11B1
SCHEMBL28918549 0.88 MAOB (0.72) MAOBGAAALDH1A1HPGDHSD11B1
SCHEMBL15065669 0.88 MAOB (0.69) MAOBGAAALDH1A1HPGDHSD11B1
SCHEMBL28823131 0.87 MAOB (0.67) MAOBGAAALDH1A1HPGDHSD11B1
SCHEMBL28823163 0.86 MAOB (0.66) MAOBGAAALDH1A1HPGDHSD11B1
SCHEMBL28918835 0.86 MAOB (0.77) MAOBGAAALDH1A1HPGDHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368333-B Ibuprofen-coumarin skeleton-containing compound and application thereof 湖北医药学院 2024-11-19 CN disclosed
CN-115368333-A Compound containing ibuprofen-coumarin skeleton and application thereof 湖北医药学院 2022-11-22 CN disclosed