Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.60 |
| ▸ | MAOA | P21397 | 7/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA4 | P22748 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.59 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6416335 | 0.90 | MAOB (0.57) | MAOBMAOACA12CA2CA4 | |
| SCHEMBL30110285 | 0.89 | MAOB (0.71) | MAOBMAOACA12CA2CA4 | |
| SCHEMBL6418716 | 0.89 | SLC16A3 (0.71) | MAOBMAOACA12CA2CA4 | |
| SCHEMBL31206473 | 0.88 | MAOB (0.60) | MAOBMAOACA12CA2CA4 | |
| SCHEMBL6420522 | 0.88 | MAOB (0.60) | MAOBMAOACA12CA2CA4 | |
| SCHEMBL6420916 | 0.84 | MAOB (0.76) | MAOBMAOACA12CA2CA4 | |
| SCHEMBL455614 | 0.84 | ALDH1A1 (0.76) | MAOBMAOACA12CA2CA4 | |
| SCHEMBL30023219 | 0.79 | SLC16A3 (0.82) | MAOBMAOACA12CA2CA4 | |
| SCHEMBL6416124 | 0.79 | KDM4E (0.71) | MAOBMAOACA12CA2CA4 | |
| SCHEMBL6416333 | 0.78 | MAOB (0.57) | MAOBMAOACA12CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005118584-A2 | SAFRAMYCIN ANALOGS AS THERAPEUTIC AGENTS IN THE TREATMENT OF CANCER | AXYS PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |