Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.63 |
| ▸ | TOP1 | P11387 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.57 |
| ▸ | AHR | P35869 | 2/20 | 0.57 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.57 |
| ▸ | VDR | P11473 | 1/20 | 0.57 |
| ▸ | ACACA | Q13085 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914795 | 0.89 | KDM4E (0.59) | ACHEADORA2ATOP1ABCB1ABCG2 | |
| SCHEMBL28510601 | 0.87 | ACHE (0.69) | ACHEADORA2ATOP1ABCB1ABCG2 | |
| SCHEMBL4817642 | 0.86 | KDM4E (0.65) | ACHEADORA2ATOP1ABCB1ABCG2 | |
| SCHEMBL28506567 | 0.85 | KDM4E (0.71) | ACHEADORA2ACYP1A2ACACAHPGD | |
| Hydrochloric Acid SCHEMBL29874770 | 0.84 | KDM4E (0.69) | ACHEADORA2ACYP1A2ACACAHPGD | |
| Hydrochloric Acid SCHEMBL29874996 | 0.84 | KDM4E (0.69) | ACHEADORA2ACYP1A2ACACAHPGD | |
| Hydrochloric Acid SCHEMBL29874842 | 0.84 | KDM4E (0.69) | ACHEADORA2ACYP1A2ACACAHPGD | |
| SCHEMBL4252226 | 0.84 | TOP1 (0.51) | ACHEADORA2ATOP1ABCB1ABCG2 | |
| SCHEMBL4246554 | 0.84 | KDM4E (0.51) | ACHEADORA2ATOP1CYP1A2CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL4825130 | 0.84 | MAPT (0.51) | ACHEADORA2ATOP1ABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4096666-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE, NEURODEVELOPMENTAL, MYODEGENERATIVE, AND LYSOSOMAL STORAGE DISORDERS | Georgetown University (US) | 2022-12-07 | — | — | EP | disclosed |