Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 5/20 | 0.41 |
| ▸ | CCR8 | P51685 | 5/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.41 |
| ▸ | CCR5 | P51681 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30083108 | 0.95 | TDP1 (0.49) | TDP1PDE4BCCR1CCR8HSP90AA1 | |
| SCHEMBL28959860 | 0.83 | PARP1 (0.35) | TDP1MAPTKDM4ESMN1; SMN2RAB9A | |
| SCHEMBL30112757 | 0.83 | PARP1 (0.35) | TDP1MAPTKDM4ESMN1; SMN2RAB9A | |
| Trifluoromethanesulfonic Acid SCHEMBL30414327 | 0.82 | TDP1 (0.47) | TDP1PDE4BCCR1CCR8HSP90AA1 | |
| SCHEMBL28713857 | 0.78 | LMNA (0.37) | TDP1LMNA | |
| SCHEMBL29009663 | 0.77 | PARP1 (0.38) | TDP1MAPTTSHRRAB9AMEN1 | |
| SCHEMBL30413989 | 0.77 | PARP1 (0.38) | TDP1MAPTTSHRRAB9AMEN1 | |
| SCHEMBL30112742 | 0.76 | CCR1 (0.49) | TDP1CCR1CCR8HSP90AA1CCR5 | |
| SCHEMBL12789731 | 0.73 | TDP1 (0.53) | TDP1PDE4BCCR1CCR8HSP90AA1 | |
| SCHEMBL28639455 | 0.72 | FABP3 (0.36) | TDP1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028504-B | Preparation method and application of 2, 9-diaryl substituted o-phenanthroline and cobalt complex thereof | 南开大学（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-110028504-B | Preparation method and application of 2, 9-diaryl substituted o-phenanthroline and cobalt complex thereof | 南开大学（CN） | 2023-01-13 | — | — | CN | disclosed |