SCHEMBL30112704

SCHEMBL30112704

[N-]=[N+]=C1C(=O)c2ccc(C(=O)NCCOCCOCCCCCCCl)cc2C12c1ccc(N3CC(O)C3)cc1Oc1cc(N3CC(O)C3)ccc12

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NT5E P21589 1/20 0.32
▸ OPRM1 P35372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29250150 1.00 NT5E (0.32) NT5EOPRM1
SCHEMBL30112687 0.94 OPRM1 (0.31) NT5EOPRM1
SCHEMBL18493212 0.92 OPRM1 (0.34) NT5EOPRM1
SCHEMBL30112730 0.92 HDAC6 (0.32) NT5EOPRM1
SCHEMBL30112637 0.92 OPRM1 (0.33) OPRM1
SCHEMBL29250191 0.92 HDAC6 (0.32) NT5EOPRM1
SCHEMBL30112684 0.91 OPRM1 (0.31) OPRM1
SCHEMBL29250147 0.91 OPRM1 (0.32) NT5EOPRM1
SCHEMBL30112626 0.91 OPRM1 (0.31) NT5EOPRM1
SCHEMBL30112711 0.91 OPRM1 (0.32) NT5EOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4655355-A1 PHOTOACTIVE FLUORESCENT COMPOUNDS AND USE THEREOF FOR LABELING OF PROTEINS Eikon Therapeutics, Inc. (US) 2025-12-03 — — EP disclosed
WO-2024159100-A1 PHOTOACTIVE FLUORESCENT COMPOUNDS AND USE THEREOF FOR LABELING OF PROTEINS EIKON THERAPEUTICS, INC. (US) 2024-08-02 — — WO disclosed
EP-4377311-A1 2-DIAZO-3-OXO-2,3-DIHYDROSPIRO[INDENE-1,9'-XANTHENE] DERIVATIVES AND SIMILAR COMPOUNDS AS PHOTOACTIVE FLUORESCENT COMPOUNDS FOR PROTEIN LABELING Eikon Therapeutics Inc. (US) 2024-06-05 — — EP disclosed
US-20230086732-A1 PHOTOACTIVE FLUORESCENT COMPOUNDS AND USE THEREOF FOR LABELING OF PROTEINS EIKON THERAPEUTICS INC (US) 2023-03-23 — — US disclosed
WO-2023009503-A1 2-DIAZO-3-OXO-2,3-DIHYDROSPIRO[INDENE-1,9'-XANTHENE] DERIVATIVES AND SIMILAR COMPOUNDS AS PHOTOACTIVE FLUORESCENT COMPOUNDS FOR PROTEIN LABELING EIKON THERAPEUTICS INC. (US) 2023-02-02 — — WO disclosed
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