SCHEMBL30112831

SCHEMBL30112831

C[C@@H](O)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 1/20 0.41
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ CTSC P53634 3/20 0.38
▸ CALCRL Q16602 1/20 0.38
▸ REN P00797 1/20 0.37
▸ STAT3 P40763 3/20 0.35
▸ KEAP1 Q14145 1/20 0.35
▸ CDYL2 Q8N8U2 1/20 0.34
▸ CDYL Q9Y232 1/20 0.34
▸ PRCP P42785 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38657878 0.95 CALCRL (0.43) DPP7MEN1KMT2ACTSCCALCRL
SCHEMBL29530970 0.91 DPP7 (0.42) DPP7MEN1KMT2ACTSCCALCRL
SCHEMBL38658785 0.90 MAGI3 (0.44) DPP7CALCRLRENKEAP1
SCHEMBL31257033 0.89 MEN1 (0.47) MEN1KMT2ACALCRLRENCDYL2
SCHEMBL31688177 0.89 PDCD1LG2 (0.45) DPP7MEN1KMT2ACTSCCALCRL
SCHEMBL30844378 0.88 DPP7 (0.43) DPP7MEN1KMT2ACTSCCALCRL
SCHEMBL30242278 0.87 MEN1 (0.42) DPP7MEN1KMT2ACTSCCALCRL
SCHEMBL29475359 0.86 DPP7 (0.39) DPP7MEN1KMT2ACTSCCALCRL
SCHEMBL30910373 0.86 KMT2A (0.46) DPP7MEN1KMT2ACTSCPRCP
SCHEMBL29630487 0.86 KMT2A (0.46) DPP7MEN1KMT2ACTSCPRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11820804-B2 Peptide-based inhibitors of growth hormone action and methods of use thereof OHIO UNIVERSITY (US) 2023-11-21 — — US claimed
US-20230085176-A1 PEPTIDE-BASED INHIBITORS OF GROWTH HORMONE ACTION AND METHODS OF USE THEREOF OHIO UNIVERSITY (US) 2023-03-16 — — US claimed
US-11524986-B2 Peptide-based inhibitors of growth hormone action and methods of use thereof OHIO UNIVERSITY (US) 2022-12-13 — — US claimed
US-11820804-B2 Peptide-based inhibitors of growth hormone action and methods of use thereof OHIO UNIVERSITY (US) 2023-11-21 — — US disclosed
US-20230085176-A1 PEPTIDE-BASED INHIBITORS OF GROWTH HORMONE ACTION AND METHODS OF USE THEREOF OHIO UNIVERSITY (US) 2023-03-16 — — US disclosed
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